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Home > TX Providers > Radiation Oncologists

Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc

(83 Ratings)

Specializes in: Radiation Oncology

Duke University School of Medicine (2004)

1515 Holcombe Boulevard Unit 1202
Houston, TX 77030

(713) 563-8495

Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc is a radiation oncologist in Houston, TX specializing in radiation oncology. She graduated from Duke University School of Medicine in 2004 and has 22 years of experience. Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc is affiliated with The University of Texas MD Anderson Cancer Center.

Office Locations

1515 Holcombe Boulevard Unit 1202
Houston, TX 77030

(713) 563-8495

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In The News

“"We have been waiting for the results from this trial for quite some time for the input it can provide with regard to who we can provide pelvic radiation to in our clinics," said ASTRO discussant...”—"Survival Benefit Evades Pelvic Radiation in Less Aggressive Prostate Cancer", MedPage Today, October 2025

“Study discussant Karen Hoffman, MD, MPH, of the University of Texas MD Anderson Cancer Center in Houston, noted that "given the heterogeneity of prostate cancer, it is critical that we personalize...”—"Hormone Therapy Added to Radiotherapy Benefits Some With Recurrent Prostate Cancer", MedPage Today, September 2025

“Interestingly, the incidence of physician-reported lymphedema and grade 2 toxicity was significantly lower in patients who received hypofractionated RT, said Karen E. Hoffman, MD, of the University...”—"No Improvement in Lymphedema With Hypofractionated Nodal RT for Breast Cancer", MedPage Today, October 2024

Medicare Procedure and Patient Information

2012 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2012 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	407
radiation therapy	24

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	299

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	123
Female	52

**Ethnicity**
Non-Hispanic White	134
Black	17
Hispanic	11
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	110
From 75 to 84	48
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2013

Hypertension	73
High Cholesterol	65
Stroke	0
Ischemic Heart Disease	38
Depression	15
Chronic Kidney Disease	21
Asthma	8
Osteoperosis	10
Atrial Fibrilation	9
Heart Failure	15
Chronic Obstructive Pulmonary Disease	8
Diabetes	29
Dementia	0
Cancer	75

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2014 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	390
radiation therapy	13

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	143
Female	47

**Ethnicity**
Non-Hispanic White	141
Black	28
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	128
From 75 to 84	44
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2014

Hypertension	69
High Cholesterol	61
Stroke	0
Ischemic Heart Disease	39
Depression	15
Chronic Kidney Disease	26
Asthma	7
Osteoperosis	11
Atrial Fibrilation	8
Heart Failure	17
Chronic Obstructive Pulmonary Disease	8
Diabetes	27
Dementia	0
Cancer	75

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2015 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	264
radiation therapy	12

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	270
Female	116

**Ethnicity**
Non-Hispanic White	296
Black	44
Hispanic	24
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	252
From 75 to 84	104
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2015

Hypertension	71
High Cholesterol	62
Stroke	0
Ischemic Heart Disease	36
Depression	17
Chronic Kidney Disease	27
Asthma	9
Osteoperosis	7
Atrial Fibrilation	9
Heart Failure	12
Chronic Obstructive Pulmonary Disease	7
Diabetes	24
Dementia	6
Cancer	75

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2016 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	299
radiation therapy	20

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	132
Female	67

**Ethnicity**
Non-Hispanic White	145
Black	25
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	120
From 75 to 84	59
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2016

Hypertension	69
High Cholesterol	60
Stroke	0
Ischemic Heart Disease	31
Depression	19
Chronic Kidney Disease	31
Asthma	10
Osteoperosis	13
Atrial Fibrilation	10
Heart Failure	11
Chronic Obstructive Pulmonary Disease	6
Diabetes	30
Dementia	9
Cancer	75

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	158

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	69
Female	44

**Ethnicity**
Non-Hispanic White	76
Black	18
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	65
From 75 to 84	0
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2017

Hypertension	70
High Cholesterol	52
Stroke	0
Ischemic Heart Disease	33
Depression	26
Chronic Kidney Disease	28
Asthma	0
Osteoperosis	13
Atrial Fibrilation	0
Heart Failure	13
Chronic Obstructive Pulmonary Disease	11
Diabetes	26
Dementia	12
Cancer	75

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2018 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	200
radiation therapy	15

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	46
Female	70

**Ethnicity**
Non-Hispanic White	80
Black	16
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	80
From 75 to 84	0
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2018

Hypertension	69
High Cholesterol	56
Stroke	0
Ischemic Heart Disease	32
Depression	24
Chronic Kidney Disease	29
Asthma	0
Osteoperosis	14
Atrial Fibrilation	0
Heart Failure	11
Chronic Obstructive Pulmonary Disease	9
Diabetes	25
Dementia	11
Cancer	75

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2019 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	248
radiation therapy	14

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	90
Female	74

**Ethnicity**
Non-Hispanic White	124
Black	19
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	112
From 75 to 84	37
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2019

Hypertension	65
High Cholesterol	56
Stroke	0
Ischemic Heart Disease	34
Depression	19
Chronic Kidney Disease	31
Asthma	10
Osteoperosis	13
Atrial Fibrilation	0
Heart Failure	16
Chronic Obstructive Pulmonary Disease	9
Diabetes	26
Dementia	0
Cancer	75

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2020 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	195
radiation therapy	12

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	124
Female	59

**Ethnicity**
Non-Hispanic White	136
Black	16
Hispanic	17
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	119
From 75 to 84	52
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2020

Hypertension	67
High Cholesterol	62
Stroke	0
Ischemic Heart Disease	36
Depression	20
Chronic Kidney Disease	31
Asthma	10
Osteoperosis	8
Atrial Fibrilation	7
Heart Failure	14
Chronic Obstructive Pulmonary Disease	7
Diabetes	30
Dementia	7
Cancer	75

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2021 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	289
radiation therapy	13

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	91
Female	82

**Ethnicity**
Non-Hispanic White	132
Black	21
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	103
From 75 to 84	53
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2021

Hypertension	72
High Cholesterol	68
Stroke	0
Ischemic Heart Disease	35
Depression	24
Chronic Kidney Disease	36
Asthma	10
Osteoperosis	13
Atrial Fibrilation	7
Heart Failure	13
Chronic Obstructive Pulmonary Disease	8
Diabetes	28
Dementia	0
Cancer	75

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX during 2022 were radiation therapy.

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

doctor visit	170
radiation therapy	13

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	64
Female	69

**Ethnicity**
Non-Hispanic White	103
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	79
From 75 to 84	0
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc in 2022

Hypertension	75
High Cholesterol	75
Stroke	9
Ischemic Heart Disease	23
Depression	15
Chronic Kidney Disease	14
Asthma	11
Osteoperosis	20
Atrial Fibrilation	0
Heart Failure	10
Chronic Obstructive Pulmonary Disease	9
Diabetes	24
Dementia	0
Cancer	75

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2012 - 2022

Volume of procedures performed by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc for Medicare patients.

The highest averages for the top procedures that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated as a radiation oncologist in Houston, TX were radiation therapy.

doctor visit	265
radiation therapy	15

Average Medicare Patient Data From 2012 - 2022

Information about Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc.

**Gender**
Male	104
Female	61

**Ethnicity**
Black / African American	18
Asian / Pacific Islander	0
Non-Hispanic White	124
Native American / Alaskan Native	0
Hispanic	4
Other	0

**Age**
75 to 84	36
85 and over	0
Less than 65	0
65 to 74	106

Average of Total of Conditions of Medicare patients treated by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc From 2012 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc treated were cancer, hypertension, high cholesterol and ischemic heart disease.

Hypertension	63
High Cholesterol	56
Stroke	0
Ischemic Heart Disease	30
Depression	17
Chronic Kidney Disease	24
Asthma	6
Osteoporosis	11
Heart Failure	12
Chronic Obstructive Pulmonary Disease	7
Diabetes	24
Atrial Fibrillation	4
Dementia	4
Cancer	68

Education & Training

Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc graduated from Duke University School of Medicine in 2004. She completed residency at Georgetown University Hospital. She is certified by the Texas State Board of Medical Examiners and has a state license in Massachusetts.

Medical School: Duke University School of Medicine (2004)

Residency: Georgetown University Hospital (2005)

Board Certification: Texas State Board of Medical Examiners (2009)

Licensed In: Massachusetts

Affiliations & Hospitals

Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc is associated with these hospitals and organizations:

The University of Texas MD Anderson Cancer Center

Ratings & Reviews

Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc has an exceptional overall rating with an average of 4.85 out of 5 stars based on 83 ratings. We collect ratings and reviews of Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc from all over the web to help you find the right in Houston, TX.

4.85

Overall Rating

(83 Ratings)

Leave a Review

General Payments

These charts describe general payments received by Dr. Karen Elizabeth Hoffman, MD, MPH, MHSc. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Astellas Pharma US Inc	$3,550 $3,550
Pfizer Inc.	$3,313 $3,313
Siemens Medical Solutions USA, Inc.	$1,875 Eclipse Treatment Planning System for External Beam Radiation Therapy $1,435	Varian Treatment $309	$132
Sirtex Medical Inc	$189 SIR-Spheres microspheres $189
Janssen Biotech, Inc.	$135 Balversa $135
Other	$297 XTANDI $104	Abraxane $54	ACCLARENT SE Inflation Device $14	$125

**Types of Payments**
Travel and Lodging	$4,230
Consulting Fee	$2,000
Honoraria	$2,000
Food and Beverage	$1,129

Biography

Dr. Karen Hoffman specializes in radiation oncology. Before performing her residency at Harvard Radiation Oncology Program and Georgetown University Hospital, Dr. Hoffman attended Duke University School of Medicine. The average patient rating for Dr. Hoffman is 5.0 stars (out of 5). Awards and/or distinctions Dr. Hoffman has received include The Dr. Karen E. Hoffman Radiation Therapy Education Fund/Endowment; Duke Symposium Poster Presentation Award, Duke University; and Clinical Research Fellow, National Institutes of Health. She is professionally affiliated with The University of Texas MD Anderson Cancer Center.